VWA domain of S5a restricts the ability to bind ubiquitin and Ubl to the 26S proteasome

The 26S proteasome recognizes a vast number of ubiquitin-dependent degradation signals linked to various substrates. This recognition is mediated mainly by the stoichiometric proteasomal resident ubiquitin receptors S5a and Rpn13, which harbor ubiquitin-binding domains. Regulatory steps in substrate...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Piterman, Ravit, Braunstein, Ilana, Isakov, Elada, Ziv, Tamar, Navon, Ami, Cohen, Shenhav, Stanhill, Ariel
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263443/
https://ncbi.nlm.nih.gov/pubmed/25318673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-11-0697
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