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VWA domain of S5a restricts the ability to bind ubiquitin and Ubl to the 26S proteasome

The 26S proteasome recognizes a vast number of ubiquitin-dependent degradation signals linked to various substrates. This recognition is mediated mainly by the stoichiometric proteasomal resident ubiquitin receptors S5a and Rpn13, which harbor ubiquitin-binding domains. Regulatory steps in substrate...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Piterman, Ravit, Braunstein, Ilana, Isakov, Elada, Ziv, Tamar, Navon, Ami, Cohen, Shenhav, Stanhill, Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263443/
https://ncbi.nlm.nih.gov/pubmed/25318673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-11-0697
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