Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β

BACKGROUND: Surfactant protein D (SP-D) can regulate both innate and adaptive immunity. Recently, SP-D has been shown to contribute to the pathogenesis of airway allergic inflammation and bleomycin-induced pulmonary fibrosis. However, in allergic airways disease, the role of SP-D in airway remodelin...

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Bibliographische Detailangaben
Veröffentlicht in:Respir Res
Hauptverfasser: Ogawa, Hirohisa, Ledford, Julie G, Mukherjee, Sambuddho, Aono, Yoshinori, Nishioka, Yasuhiko, Lee, James J, Izumi, Keisuke, Hollingsworth, John W
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262976/
https://ncbi.nlm.nih.gov/pubmed/25472740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0143-9
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