Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β

BACKGROUND: Surfactant protein D (SP-D) can regulate both innate and adaptive immunity. Recently, SP-D has been shown to contribute to the pathogenesis of airway allergic inflammation and bleomycin-induced pulmonary fibrosis. However, in allergic airways disease, the role of SP-D in airway remodelin...

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Bibliografiske detaljer
Udgivet i:Respir Res
Main Authors: Ogawa, Hirohisa, Ledford, Julie G, Mukherjee, Sambuddho, Aono, Yoshinori, Nishioka, Yasuhiko, Lee, James J, Izumi, Keisuke, Hollingsworth, John W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262976/
https://ncbi.nlm.nih.gov/pubmed/25472740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0143-9
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