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HLA-DQ Allele Competition in Narcolepsy: A Comment on Tafti et al. DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe

STUDY OBJECTIVES: Although HLA-DQB1*06:02 is the strongest predisposing genetic factor for narcolepsy, the effect of this gene must be considered alongside that of its polymorphic partner, DQA1. In this paper, we extend an analysis of the effect of HLA-DQB1 on narcolepsy risk published recently by T...

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Detalhes bibliográficos
Publicado no:Sleep
Main Authors: Ollila, Hanna M., Fernandez-Vina, Marcelo, Mignot, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262948/
https://ncbi.nlm.nih.gov/pubmed/25325462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.4342
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