Complex HLA-DR and -DQ Interactions Confer Risk of Narcolepsy-Cataplexy in Three Ethnic Groups

Human narcolepsy-cataplexy, a sleep disorder associated with a centrally mediated hypocretin (orexin) deficiency, is tightly associated with HLA-DQB1*0602. Few studies have investigated the influence that additional HLA class II alleles have on susceptibility to this disease. In this work, 1,087 con...

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Главные авторы: Mignot, Emmanuel, Lin, Ling, Rogers, William, Honda, Yutaka, Qiu, Xiaohong, Lin, Xiaoyan, Okun, Michele, Hohjoh, Hirohiko, Miki, Tetsuro, Hsu, Susan H., Leffell, Mary S., Grumet, F. Carl, Fernandez-Vina, Marcelo, Honda, Makoto, Risch, Neil
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society of Human Genetics 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1274481/
https://ncbi.nlm.nih.gov/pubmed/11179016
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