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Netrin-1 Improves post-Injury Cardiac Function in vivo via DCC/NO-dependent Preservation of Mitochondrial Integrity, While Attenuating Autophagy

Reperfusion injury of the heart is a severe complication of angioplasty treatment of acute myocardial ischemia, for which no therapeutics are currently available. The present study aimed to identify whether and how a novel protein netrin-1 induces cardioprotection in vivo during ischemia/reperfusion...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Bouhidel, Jalaleddinne Omar, Wang, Ping, Siu, Kin Lung, Li, Hong, Youn, Ji Youn, Cai, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262720/
https://ncbi.nlm.nih.gov/pubmed/24928309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.06.005
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