In Vitro Synergistic Action of Geldanamycin- and Docetaxel-Containing HPMA Copolymer-RGDfK Conjugates against Ovarian Cancer()

This study describes the synthesis, characterization, and in vitro evaluation of a combination therapy utilizing HPMA copolymer-RGDfK conjugates. HPMA copolymer-RGDfK conjugates bearing either aminohexylgeldanamycin or docetaxel were synthesized and characterized. Stability was evaluated in physiolo...

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Publicat a:Macromol Biosci
Autors principals: Larson, Nate, Roberts, Sarah, Ray, Abhijit, Buckway, Brandon, Cheney, Darwin L., Ghandehari, Hamidreza
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262670/
https://ncbi.nlm.nih.gov/pubmed/25185891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201400360
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