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A protocol for evaluation of Rett Syndrome symptom improvement by metabolic modulators in Mecp2-mutant mice
Mouse models recapitulate many symptoms of Rett Syndrome, an X-linked disorder caused by mutations in methyl-CpG-binding protein 2 (MECP2). The study of Mecp2-null male mice has provided insight into pathogenesis of the disorder; most recently, dysregulation of cholesterol and lipid metabolism. Peri...
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| Publicado no: | Curr Protoc Mouse Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4261228/ https://ncbi.nlm.nih.gov/pubmed/25506514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470942390.mo130157 |
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