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mTOR signaling in tumorigenesis

mTOR (the mechanistic target of rapamycin) is an atypical serine/threonine kinase involved in regulating major cellular functions including growth and proliferation. Deregulations of the mTOR signaling pathway is one of the most commonly observed pathological alterations in human cancers. To this en...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochim Biophys Acta
Main Authors: Xu, Kai, Liu, Pengda, Wei, Wenyi
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261029/
https://ncbi.nlm.nih.gov/pubmed/25450580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2014.10.007
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