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mTOR signaling in tumorigenesis

mTOR (the mechanistic target of rapamycin) is an atypical serine/threonine kinase involved in regulating major cellular functions including growth and proliferation. Deregulations of the mTOR signaling pathway is one of the most commonly observed pathological alterations in human cancers. To this en...

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Detalles Bibliográficos
Publicado en:Biochim Biophys Acta
Main Authors: Xu, Kai, Liu, Pengda, Wei, Wenyi
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261029/
https://ncbi.nlm.nih.gov/pubmed/25450580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2014.10.007
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