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By-Product Formation in Repetitive PCR Amplification of DNA Libraries during SELEX

The selection of nucleic acid aptamers is an increasingly important approach to generate specific ligands binding to virtually any molecule of choice. However, selection-inherent amplification procedures are prone to artificial by-product formation that prohibits the enrichment of target-recognizing...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Tolle, Fabian, Wilke, Julian, Wengel, Jesper, Mayer, Günter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260880/
https://ncbi.nlm.nih.gov/pubmed/25490402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114693
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