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Resistance to vemurafenib resulting from a novel mutation in the BRAFV600E kinase domain

Resistance to the BRAF inhibitor vemurafenib poses a significant problem for the treatment of BRAFV600E-positive melanomas. It is therefore critical to prospectively identify all vemurafenib-resistance mechanisms prior to their emergence in the clinic. The vemurafenib-resistance mechanisms described...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pigment Cell Melanoma Res
Egile Nagusiak: Wagenaar, Timothy R., Ma, Leyuan, Roscoe, Benjamin, Park, Sung Mi, Bolon, Daniel N., Green, Michael R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260813/
https://ncbi.nlm.nih.gov/pubmed/24112705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12171
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