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Dabrafenib in BRAFV600-mutated anaplastic pleomorphic xanthoastrocytoma

Pleomorphic xanthoastrocytoma (PXA) is a rare brain tumor. Anaplastic features are found in 20–30% of cases of PXA and are associated with poor outcomes. Typical treatment is with gross total resection, followed by radiation therapy and cytotoxic chemotherapy at relapse. BRAFV600 mutations have been...

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Foilsithe in:CNS Oncol
Main Authors: Brown, Nicholas F, Carter, Thomas, Mulholland, Paul
Formáid: Artigo
Teanga:Inglês
Foilsithe: Future Medicine Ltd 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027936/
https://ncbi.nlm.nih.gov/pubmed/27781490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2016-0031
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