Centrosome-declustering drugs mediate a two-pronged attack on interphase and mitosis in supercentrosomal cancer cells

Classical anti-mitotic drugs have failed to translate their preclinical efficacy into clinical response in human trials. Their clinical failure has challenged the notion that tumor cells divide frequently at rates comparable to those of cancer cells in vitro and in xenograft models. Given the prepon...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Pannu, V, Rida, P C G, Celik, B, Turaga, R C, Ogden, A, Cantuaria, G, Gopalakrishnan, J, Aneja, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260758/
https://ncbi.nlm.nih.gov/pubmed/25412316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.505
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