Llwytho...

Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis

Nek5 is a poorly characterized member of the NIMA-related kinase family, other members of which play roles in cell cycle progression and primary cilia function. Here, we show that Nek5, similar to Nek2, localizes to the proximal ends of centrioles. Depletion of Nek5 or overexpression of kinase-inact...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Prosser, Suzanna L., Sahota, Navdeep K., Pelletier, Laurence, Morrison, Ciaran G., Fry, Andrew M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427792/
https://ncbi.nlm.nih.gov/pubmed/25963817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412099
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