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Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis
Nek5 is a poorly characterized member of the NIMA-related kinase family, other members of which play roles in cell cycle progression and primary cilia function. Here, we show that Nek5, similar to Nek2, localizes to the proximal ends of centrioles. Depletion of Nek5 or overexpression of kinase-inact...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4427792/ https://ncbi.nlm.nih.gov/pubmed/25963817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412099 |
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