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Pharmaco-Proteomic Study of Hydroxyurea-Induced Modifications in the Sickle Red Blood Cell Membrane Proteome

Hydroxyurea (HU) is an effective oral drug for the management of homozygous sickle cell anemia (SS) in part because it increases fetal hemoglobin (HbF) levels within sickle red blood cells (RBCs) and thus reduces sickling. However, results from the Multicenter Study of HU suggested that clinical sym...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: GHATPANDE, SWATI S., CHOUDHARY, PANKAJ K., QUINN, CHARLES T., GOODMAN, STEVEN R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260454/
https://ncbi.nlm.nih.gov/pubmed/18849548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0805-S-149
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