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Pharmaco-Proteomic Study of Hydroxyurea-Induced Modifications in the Sickle Red Blood Cell Membrane Proteome

Hydroxyurea (HU) is an effective oral drug for the management of homozygous sickle cell anemia (SS) in part because it increases fetal hemoglobin (HbF) levels within sickle red blood cells (RBCs) and thus reduces sickling. However, results from the Multicenter Study of HU suggested that clinical sym...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Biol Med (Maywood)
Main Authors: GHATPANDE, SWATI S., CHOUDHARY, PANKAJ K., QUINN, CHARLES T., GOODMAN, STEVEN R.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260454/
https://ncbi.nlm.nih.gov/pubmed/18849548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0805-S-149
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