Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.
Apolipoprotein B is synthesized by the intestine and the liver in mammals, where it serves as the main structural component in the formation of chylomicrons and very low density lipoproteins, respectively. Apolipoprotein B is also expressed in mammalian fetal membranes. To examine the consequences o...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1995
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7878058/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1774 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|