A pathogenic progranulin mutation and C9orf72 repeat expansion in a family with frontotemporal dementia

AIMS: Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disease and is the second most common form of young onset dementia after Alzheimer's disease (AD). An autosomal dominant pattern of inheritance is present in around 25–50% of FTLD cases indicating a strong genetic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropathol Appl Neurobiol
Prif Awduron: Lashley, Tammaryn, Rohrer, Jonathan D, Mahoney, Colin, Gordon, Elizabeth, Beck, Jon, Mead, Simon, Warren, Jason, Rossor, Martin, Revesz, Tamas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2014
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260146/
https://ncbi.nlm.nih.gov/pubmed/24286341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12100
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg