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Minireview: Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome’s potential to cause inflammation

Immunodeficiencies can lead to alterations of the gut microbiome that render it pathogenic and capable of transmitting disease to naïve hosts. Here we review the role of Toll-like receptor (TLR) 5, the innate receptor for bacterial flagellin, in immune responses to the normal gut microbiota with a f...

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Detalhes bibliográficos
Publicado no:Immunol Lett
Main Authors: Leifer, Cynthia A., McConkey, Cameron, Li, Sha, Chassaing, Benoit, Gewirtz, Andrew T., Ley, Ruth E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259828/
https://ncbi.nlm.nih.gov/pubmed/25284610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2014.07.017
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