Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut

Gut mucosal barrier breakdown and inflammation have been associated with high levels of flagellin, the principal bacterial flagellar protein. Although several gut commensals can produce flagella, flagellin levels are low in the healthy gut, suggesting the existence of control mechanisms. We find tha...

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Main Authors: Cullender, Tyler C., Chassaing, Benoit, Janzon, Anders, Kumar, Krithika, Muller, Catherine, Werner, Jeffrey J., Angenent, Largus T., Bell, M. Elizabeth, Hay, Anthony G., Peterson, Daniel A., Walter, Jens, Vijay-Kumar, Matam, Gewirtz, Andrew T., Ley, Ruth E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920589/
https://ncbi.nlm.nih.gov/pubmed/24237702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.10.009
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