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Intestinal Epithelial cell Toll-like Receptor 5 Regulates the Intestinal Microbiota to Prevent Low-grade Inflammation and Metabolic Syndrome in Mice

BACKGROUND & AIMS: Mice lacking the receptor toll-like receptor 5 (TLR5-null mice), which recognizes flagellin, have an altered intestinal microbiota composition compared to wild-type mice; they develop low-grade inflammation, metabolic syndrome, and are prone to colitis. The relative roles of i...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Chassaing, Benoit, Ley, Ruth E., Gewirtz, Andrew T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253564/
https://ncbi.nlm.nih.gov/pubmed/25172014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.08.033
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