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Epigenetic Enzymes Are the Therapeutic Targets for CD4(+)CD25(+/high)Foxp3(+) Regulatory T Cells

CD4(+)CD25(+/high)Foxp3(+) regulatory T cells (Tregs) are a subset of CD4(+) T cells that play an essential role in maintaining peripheral immune tolerance. Several transcriptional co-factors have been recently identified, which form complexes with Tregs transcription factor Foxp3 and contribute in...

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Détails bibliographiques
Publié dans:Transl Res
Auteurs principaux: Pastrana, Jahaira Lopez, Shao, Ying, Chernaya, Valeria, Wang, Hong, Yang, Xiao-feng
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259825/
https://ncbi.nlm.nih.gov/pubmed/25193380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2014.08.001
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