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Age-related changes in CD4(+)CD25(+)FOXP3(+) regulatory T cells and their relationship with lung cancer

OBJECTIVES: CD4(+)CD25(+)FOXP3(+) regulatory T cells (Treg) inhibit the anti-tumour immune response and reduce the effect of cancer immunotherapy. Although studies have demonstrated that the number and suppressive activity of Treg increase with age, it is not clear whether these changes correlate wi...

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Udgivet i:PLoS One
Main Authors: Hou, Pan-Fei, Zhu, Li-Jing, Chen, Xiao-Ying, Qiu, Zhu-Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333862/
https://ncbi.nlm.nih.gov/pubmed/28253320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173048
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