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Age-related changes in CD4(+)CD25(+)FOXP3(+) regulatory T cells and their relationship with lung cancer

OBJECTIVES: CD4(+)CD25(+)FOXP3(+) regulatory T cells (Treg) inhibit the anti-tumour immune response and reduce the effect of cancer immunotherapy. Although studies have demonstrated that the number and suppressive activity of Treg increase with age, it is not clear whether these changes correlate wi...

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Pubblicato in:PLoS One
Autori principali: Hou, Pan-Fei, Zhu, Li-Jing, Chen, Xiao-Ying, Qiu, Zhu-Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333862/
https://ncbi.nlm.nih.gov/pubmed/28253320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173048
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