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Age-related changes in CD4(+)CD25(+)FOXP3(+) regulatory T cells and their relationship with lung cancer

OBJECTIVES: CD4(+)CD25(+)FOXP3(+) regulatory T cells (Treg) inhibit the anti-tumour immune response and reduce the effect of cancer immunotherapy. Although studies have demonstrated that the number and suppressive activity of Treg increase with age, it is not clear whether these changes correlate wi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hou, Pan-Fei, Zhu, Li-Jing, Chen, Xiao-Ying, Qiu, Zhu-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333862/
https://ncbi.nlm.nih.gov/pubmed/28253320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173048
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