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Src-dependent phosphorylation at Y406 on the thyroid hormone receptor β confers the tumor suppressor activity

Association studies suggest that the thyroid hormone receptor β1 (TRβ1) could function as a tumor suppressor in cancer cells. However, the underlying molecular mechanisms remain to be elucidated. We explored how TRβ1 acted as a tumor suppressor in breast cancer MDA cells. Proliferation and invasiven...

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Vydáno v:Oncotarget
Hlavní autoři: Park, Jeong Won, Zhao, Li, Webb, Paul, Cheng, Sheue-yann
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259401/
https://ncbi.nlm.nih.gov/pubmed/25275301
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