Genome-Wide Linkage Scan Identifies Two Novel Genetic Loci for Coronary Artery Disease: In GeneQuest Families

Coronary artery disease (CAD) is the leading cause of death worldwide. Recent genome-wide association studies (GWAS) identified >50 common variants associated with CAD or its complication myocardial infarction (MI), but collectively they account for <20% of heritability, generating a phenomena...

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Veröffentlicht in:PLoS One
Hauptverfasser: Gao, Hanxiang, Li, Lin, Rao, Shaoqi, Shen, Gongqing, Xi, Quansheng, Chen, Shenghan, Zhang, Zheng, Wang, Kai, Ellis, Stephen G., Chen, Qiuyun, Topol, Eric J., Wang, Qing K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259362/
https://ncbi.nlm.nih.gov/pubmed/25485937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113935
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