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Design of DNA Pooling to Allow Incorporation of Covariates in Rare Variants Analysis

BACKGROUND: Rapid advances in next-generation sequencing technologies facilitate genetic association studies of an increasingly wide array of rare variants. To capture the rare or less common variants, a large number of individuals will be needed. However, the cost of a large scale study using whole...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Guan, Weihua, Li, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259344/
https://ncbi.nlm.nih.gov/pubmed/25485788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114523
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