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Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation
TGFβ1 (Transforming Growth Factor-beta1) is a versatile regulator of T cell immune responses. Depending on its context in the immunological environment, TGFβ1 guides T cells toward specific activation programs including T(H)17 and regulatory T cell activities. Moreover, TGFβ signals function in immu...
Gespeichert in:
| Veröffentlicht in: | Cell Commun Signal |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258951/ https://ncbi.nlm.nih.gov/pubmed/25482031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0074-6 |
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