The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...

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Pubblicato in:Haematologica
Autori principali: Durinck, Kaat, Wallaert, Annelynn, Van de Walle, Inge, Van Loocke, Wouter, Volders, Pieter-Jan, Vanhauwaert, Suzanne, Geerdens, Ellen, Benoit, Yves, Van Roy, Nadine, Poppe, Bruce, Soulier, Jean, Cools, Jan, Mestdagh, Pieter, Vandesompele, Jo, Rondou, Pieter, Van Vlierberghe, Pieter, Taghon, Tom, Speleman, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2014
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258754/
https://ncbi.nlm.nih.gov/pubmed/25344525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.115683
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