Combination of Peptide YY(3–36) with GLP-1(7–36 amide) Causes an Increase in First-Phase Insulin Secretion after IV Glucose

CONTEXT: The combination of peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) has been proposed as a potential treatment for diabetes and obesity. However, the combined effects of these hormones, PYY(3–36) and GLP-1(7–36 amide), on glucose homeostasis are unknown. OBJECTIVE: This study sought to...

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Publicado no:J Clin Endocrinol Metab
Main Authors: Tan, Tricia M., Salem, Victoria, Troke, Rachel C., Alsafi, Ali, Field, Benjamin C. T., De Silva, Akila, Misra, Shivani, Baynes, Kevin C. R., Donaldson, Mandy, Minnion, James, Ghatei, Mohammad A., Godsland, Ian F., Bloom, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Hot Topics in Translational Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258604/
https://ncbi.nlm.nih.gov/pubmed/25144632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2143
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