Coadministration of Glucagon-Like Peptide-1 During Glucagon Infusion in Humans Results in Increased Energy Expenditure and Amelioration of Hyperglycemia

Glucagon and glucagon-like peptide (GLP)-1 are the primary products of proglucagon processing from the pancreas and gut, respectively. Giving dual agonists with glucagon and GLP-1 activity to diabetic, obese mice causes enhanced weight loss and improves glucose tolerance by reduction of food intake...

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Autori principali: Tan, Tricia M., Field, Benjamin C.T., McCullough, Katherine A., Troke, Rachel C., Chambers, Edward S., Salem, Victoria, Gonzalez Maffe, Juan, Baynes, Kevin C.R., De Silva, Akila, Viardot, Alexander, Alsafi, Ali, Frost, Gary S., Ghatei, Mohammad A., Bloom, Stephen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609580/
https://ncbi.nlm.nih.gov/pubmed/23248172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0797
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