Obesity-Associated Melanocortin-4 Receptor Mutations Are Associated With Changes in the Brain Response to Food Cues

CONTEXT: Mutations in the melanocortin-4 receptor (MC4R) represent the commonest genetic form of obesity and are associated with hyperphagia. OBJECTIVE: The aim of this study was to investigate whether melanocortin signaling modulates anticipatory food reward by studying the brain activation respons...

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Bibliografische gegevens
Gepubliceerd in:J Clin Endocrinol Metab
Hoofdauteurs: van der Klaauw, Agatha A., von dem Hagen, Elisabeth A. H., Keogh, Julia M., Henning, Elana, O'Rahilly, Stephen, Lawrence, Andrew D., Calder, Andrew J., Farooqi, I. Sadaf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2014
Onderwerpen:
JCEM Online: Advances in Genetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258603/
https://ncbi.nlm.nih.gov/pubmed/25062455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1651
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