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Role of melanocortin signalling in the preference for dietary macronutrients in human beings

BACKGROUND: Signalling though the melanocortin 4 receptor (MC4R), which is widely expressed in the hypothalamus, mediates food intake and macronutrient preference in rodents. Studies in patients with MC4R deficiency can provide insights into the role of this pathway in man. We investigated the role...

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Publicat a:Lancet
Autors principals: van der Klaauw, Agatha, Keogh, Julia, Henning, Elana, Stephenson, Cheryl, Trowse, Victoria M, Fletcher, Paul, Farooqi, Sadaf
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548551/
https://ncbi.nlm.nih.gov/pubmed/26312834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(15)60327-0
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