Gene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte development

Thymocyte development is regulated by complex signaling pathways. How these signaling cascades are coordinated remains elusive. RhoA of the Rho family small GTPases plays an important role in actin cytoskeleton organization, cell adhesion, migration, proliferation, and survival. Nonetheless, the phy...

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Pubblicato in:J Immunol
Autori principali: Zhang, Shuangmin, Konstantinidis, Diamantis G., Yang, Jun-Qi, Mizukawa, Benjamin, Kalim, Khalid, Lang, Richard A., Kalfa, Theodosia A., Yi, Zheng, Guo, Fukun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258484/
https://ncbi.nlm.nih.gov/pubmed/25398325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400839
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