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Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation

Asthma is a heterogeneous chronic airway inflammation in which Th2 and Th17 cells are key players in its pathogenesis. We have reported that RhoA of Rho GTPases orchestrated glycolysis for Th2 cell differentiation and allergic airway inflammation by the use of a conditional RhoA-deficient mouse line...

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Dades bibliogràfiques
Publicat a:J Leukoc Biol
Autors principals: Yang, Jun-Qi, Kalim, Khalid W., Li, Yuan, Zheng, Yi, Guo, Fukun
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747217/
https://ncbi.nlm.nih.gov/pubmed/31260596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A0119-025RRR
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