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STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells

Adaptive immune responses to antigens released by dying cells play a critical role in the development of autoimmunity, allograft rejection, and spontaneous as well as therapy-induced tumor rejection. Although cell death in these situations is considered sterile, various reports have implicated type...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Klarquist, Jared, Hennies, Cassandra M., Lehn, Maria A., Reboulet, Rachel A., Feau, Sonia, Janssen, Edith M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258444/
https://ncbi.nlm.nih.gov/pubmed/25385820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401869
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