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Prolonged antigen storage endows merocytic DC with enhanced capacity to prime anti-tumor responses in tumor-bearing mice
Tumor-cell vaccination with irradiated autologous tumor cells is a promising approach to activate tumor-specific T cell responses without the need for tumor antigen identification. However, uptake of dying cells by DC is generally a non-inflammatory or tolerizing event in order to prevent the develo...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021914/ https://ncbi.nlm.nih.gov/pubmed/20720209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001619 |
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