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Effects of Naturally Occuring Arginine 14 Deletion on Phospholamban Conformational Dynamics and Membrane Interactions
Phospholamban (PLN) is a single-pass membrane protein that regulates the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA). Phosphorylation of PLN at Ser16 reverses its inhibitory function under β-adrenergic stimulation, augmenting Ca(2+) uptake in the sarcoplasmic reticulum and muscle contractilit...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258429/ https://ncbi.nlm.nih.gov/pubmed/25251363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.09.007 |
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