Diversity in the pre-immune immunoglobulin repertoire of SHR lines susceptible and resistant to end organ injury

We used next-generation sequencing to identify IGH genetic variation in two closely related hypertensive rat lines that differ in susceptibility to end-organ disease (SHR-A3 and SHR-B2). The two SHR lines differ extensively at the IGH locus from the rat reference genome sequence (RRGS) and from each...

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Vydáno v:Genes Immun
Hlavní autoři: Gonzalez-Garay, Manuel L., Cranford, Stacy M., Braun, Michael C., Doris, Peter A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257902/
https://ncbi.nlm.nih.gov/pubmed/25056448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.40
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