Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility

Innate natural killer (NK) cells are diverse at the single-cell level because of variegated expressions of activating and inhibitory receptors, yet the developmental roots and functional consequences of this diversity remain unknown. Because NK cells are critical for antiviral and antitumor response...

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Veröffentlicht in:Sci Transl Med
Hauptverfasser: Strauss-Albee, Dara M., Fukuyama, Julia, Liang, Emily C., Yao, Yi, Jarrell, Justin A., Drake, Alison L., Kinuthia, John, Montgomery, Ruth R., John-Stewart, Grace, Holmes, Susan, Blish, Catherine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547537/
https://ncbi.nlm.nih.gov/pubmed/26203083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac5722
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