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Transcriptional regulation of autophagy by an FXR/CREB axis
Lysosomal degradation of cytoplasmic components by autophagy is essential for cellular survival and homeostasis under nutrient-deprived conditions(1–4). Acute regulation of autophagy by nutrient-sensing kinases is well defined(3, 5–7), but longer-term transcriptional regulation is relatively unknown...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4257899/ https://ncbi.nlm.nih.gov/pubmed/25383523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13949 |
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