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Estimation of Epistatic Variance Components and Heritability in Founder Populations and Crosses

Genetic association studies have explained only a small proportion of the estimated heritability of complex traits, leaving the remaining heritability “missing.” Genetic interactions have been proposed as an explanation for this, because they lead to overestimates of the heritability and are hard to...

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書目詳細資料
發表在:Genetics
Main Authors: Young, Alexander I., Durbin, Richard
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256760/
https://ncbi.nlm.nih.gov/pubmed/25326236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.170795
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