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Estimation of Epistatic Variance Components and Heritability in Founder Populations and Crosses

Genetic association studies have explained only a small proportion of the estimated heritability of complex traits, leaving the remaining heritability “missing.” Genetic interactions have been proposed as an explanation for this, because they lead to overestimates of the heritability and are hard to...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Young, Alexander I., Durbin, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256760/
https://ncbi.nlm.nih.gov/pubmed/25326236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.170795
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