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Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity

Glioblastoma (GBM), the most common type of primary malignant brain tumors harboring a subpopulation of stem-like cells (GSCs), is a fast-growing and often fatal tumor. Signal Transducer and Activator of Transcription 3 (STAT3) is one of the major signaling pathways in GSCs maintenance but the molec...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kim, Hong Sug, Li, Aiguo, Ahn, Susie, Song, Hua, Zhang, Wei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256660/
https://ncbi.nlm.nih.gov/pubmed/25476455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07330
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