Ion Mobility Tandem Mass Spectrometry Enhances Performance of Bottom-up Proteomics

One of the limiting factors in determining the sensitivity of tandem mass spectrometry using hybrid quadrupole orthogonal acceleration time-of-flight instruments is the duty cycle of the orthogonal ion injection system. As a consequence, only a fraction of the generated fragment ion beam is collecte...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cell Proteomics
Auteurs principaux: Helm, Dominic, Vissers, Johannes P. C., Hughes, Christopher J., Hahne, Hannes, Ruprecht, Benjamin, Pachl, Fiona, Grzyb, Arkadiusz, Richardson, Keith, Wildgoose, Jason, Maier, Stefan K., Marx, Harald, Wilhelm, Mathias, Becher, Isabelle, Lemeer, Simone, Bantscheff, Marcus, Langridge, James I., Kuster, Bernhard
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2014
Sujets:
Technological Innovation and Resources
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256517/
https://ncbi.nlm.nih.gov/pubmed/25106551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.041038
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