Ion Mobility Tandem Mass Spectrometry Enhances Performance of Bottom-up Proteomics

One of the limiting factors in determining the sensitivity of tandem mass spectrometry using hybrid quadrupole orthogonal acceleration time-of-flight instruments is the duty cycle of the orthogonal ion injection system. As a consequence, only a fraction of the generated fragment ion beam is collecte...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Helm, Dominic, Vissers, Johannes P. C., Hughes, Christopher J., Hahne, Hannes, Ruprecht, Benjamin, Pachl, Fiona, Grzyb, Arkadiusz, Richardson, Keith, Wildgoose, Jason, Maier, Stefan K., Marx, Harald, Wilhelm, Mathias, Becher, Isabelle, Lemeer, Simone, Bantscheff, Marcus, Langridge, James I., Kuster, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Technological Innovation and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256517/
https://ncbi.nlm.nih.gov/pubmed/25106551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.041038
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