Ion Mobility Tandem Mass Spectrometry Enhances Performance of Bottom-up Proteomics

One of the limiting factors in determining the sensitivity of tandem mass spectrometry using hybrid quadrupole orthogonal acceleration time-of-flight instruments is the duty cycle of the orthogonal ion injection system. As a consequence, only a fraction of the generated fragment ion beam is collecte...

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Bibliografske podrobnosti
izdano v:Mol Cell Proteomics
Main Authors: Helm, Dominic, Vissers, Johannes P. C., Hughes, Christopher J., Hahne, Hannes, Ruprecht, Benjamin, Pachl, Fiona, Grzyb, Arkadiusz, Richardson, Keith, Wildgoose, Jason, Maier, Stefan K., Marx, Harald, Wilhelm, Mathias, Becher, Isabelle, Lemeer, Simone, Bantscheff, Marcus, Langridge, James I., Kuster, Bernhard
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2014
Teme:
Technological Innovation and Resources
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256517/
https://ncbi.nlm.nih.gov/pubmed/25106551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.041038
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