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Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics

The fatal neurodegenerative disorders amyotrophic lateral sclerosis and spinal muscular atrophy are, respectively, the most common motoneuron disease and genetic cause of infant death. Various in vitro model systems have been established to investigate motoneuron disease mechanisms, in particular im...

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Publicat a:Mol Cell Proteomics
Autors principals: Hornburg, Daniel, Drepper, Carsten, Butter, Falk, Meissner, Felix, Sendtner, Michael, Mann, Matthias
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256493/
https://ncbi.nlm.nih.gov/pubmed/25193168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037291
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