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Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics

The fatal neurodegenerative disorders amyotrophic lateral sclerosis and spinal muscular atrophy are, respectively, the most common motoneuron disease and genetic cause of infant death. Various in vitro model systems have been established to investigate motoneuron disease mechanisms, in particular im...

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Foilsithe in:Mol Cell Proteomics
Main Authors: Hornburg, Daniel, Drepper, Carsten, Butter, Falk, Meissner, Felix, Sendtner, Michael, Mann, Matthias
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Biochemistry and Molecular Biology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256493/
https://ncbi.nlm.nih.gov/pubmed/25193168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037291
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